By definition,
∂x∂y2∂3f(2x+3y,xy)=∂x∂[∂y∂(∂y∂f(2x+3y,xy))]
We'll compute the derivatives from the inside out.
Let's call F(x,y)=f(2x+3y,xy) so that the innermost derivative is G(x,y)=∂y∂f(2x+3y,xy)=∂y∂F(x,y). By the chain rule
G(x,y)=∂y∂F(x,y)=f1(2x+3y,xy)∂y∂(2x+3y)+f2(2x+3y,xy)∂y∂(xy)=3f1(2x+3y,xy)+xf2(2x+3y,xy)
Here the subscript 1 means take the partial derivative of f with respect to
the first argument while holding the second argument fixed, and
the subscript 2 means take the partial derivative of f with respect to
the second argument while holding the first argument fixed.
Next call the middle derivative
H(x,y)=∂y∂(∂y∂f(2x+3y,xy)) so that
H(x,y)=∂y∂G(x,y)=∂y∂(3f1(2x+3y,xy)+xf2(2x+3y,xy))=3∂y∂(f1(2x+3y,xy))+x∂y∂(f2(2x+3y,xy))
By the chain rule (twice),
∂y∂(f1(2x+3y,xy))∂y∂(f2(2x+3y,xy))=f11(2x+3y,xy)∂y∂(2x+3y)+f12(2x+3y,xy)∂y∂(xy)=3f11(2x+3y,xy)+xf12(2x+3y,xy)=f21(2x+3y,xy)∂y∂(2x+3y)+f22(2x+3y,xy)∂y∂(xy)=3f21(2x+3y,xy)+xf22(2x+3y,xy)
so that
H(x,y)=3(3f11(2x+3y,xy)+xf12(2x+3y,xy))+x(3f21(2x+3y,xy)+xf22(2x+3y,xy))=9f11(2x+3y,xy)+6xf12(2x+3y,xy)+x2f22(2x+3y,xy)
In the last equality we used that f21(2x+3y,xy)=f12(2x+3y,xy).
The notation
f21 means first differentiate with respect to the second argument
and then differentiate with respect to the first argument. For example,
if f(x,y)=e2ysinx, then
f21(x,y)=∂x∂[∂y∂(e2ysinx)]=∂x∂[2e2ysinx]=2eycosx
Finally, we get to
∂x∂y2∂3f(2x+3y,xy)=∂x∂H(x,y)=∂x∂(9f11(2x+3y,xy)+6xf12(2x+3y,xy)+x2f22(2x+3y,xy))=9∂x∂(f11(2x+3y,xy))+6f12(2x+3y,xy)+6x∂x∂(f12(2x+3y,xy))+2xf22(2x+3y,xy)+x2∂x∂(f22(2x+3y,xy))
By three applications of the chain rule
∂x∂y2∂3f(2x+3y,xy)=9(2f111+yf112)+6f12+6x(2f121+yf122)+2xf22+x2(2f221+yf222)=6f12+2xf22+18f111+(9y+12x)f112+(6xy+2x2)f122+x2yf222
All functions on the right hand side have arguments (2x+3y,xy).