A good approximation from the graph is f(5)=0.5. We want to find a secant line whose endpoints are both very close to x=5, but that also give us clear y-values. It looks like f(5.25)≈1, and f(4.75)≈81. The secant line from x=5 to x=5.25 has approximate slope 5.25−5f(5.25)−f(5)≈.251−.5=2. The secant line from x=5 to x=4.75 has approximate slope 5−4.750.5−81=23.
The graph increases more and more quickly (gets steeper and steeper), so it makes sense that the secant line to the left of x=5 has a smaller slope than the secant line to the right of x=5. Also, if you're taking secant lines that have endpoints farther out from x=5, you'll notice that the slopes of the secant lines change quite dramatically. You have to be very, very close to x=5 to get any kind of accuracy.
If we split the difference, we might approximate the slope of the secant line to be the average of 23 and 2, which is 47.
Another way to try to figure out the tangent line is by carefully drawing it in with a ruler. This is shown here in blue:

It's much easier to take the slope of a line than a curve, and this one looks like it has slope about 1.5. However, we drew this with a computer: by hand it's much harder to draw an accurate tangent line. (That's why we need calculus!)
The actual slope of the tangent line to the function at x=5 is about 1.484. This is extremely hard to figure out just from the graph–by hand, a guess between 1.25 and 1.75 would be very accurate.